Harlan F. Reese

Publications by Year

Research Areas

Asymmetric Synthesis and Catalysis, Computational Drug Discovery Methods, Synthesis and biological activity, Melanoma and MAPK Pathways, Chemical synthesis and alkaloids

Most-Cited Works

• → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
• → The First Asymmetric Pilot-Scale Synthesis of TV-45070(2017)18 cited