Robert A. Heald
Babraham Institute(GB)Charles River Laboratories (United Kingdom)(GB)Babraham Bioscience Technologies (United Kingdom)(GB)Charles River Laboratories (Germany)(DE)Universidad de Estudios Profesionales de Ciencias y Artes(MX)
Publications by Year
Research Areas
HER2/EGFR in Cancer Research, Melanoma and MAPK Pathways, Protein Tyrosine Phosphatases, DNA Repair Mechanisms, Computational Drug Discovery Methods
Most-Cited Works
- → Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance(2021)340 cited
- → Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers(2013)317 cited
- → Potent Inhibition of Telomerase by Small-Molecule Pentacyclic Acridines Capable of Interacting with G-Quadruplexes(2001)217 cited
- → Drug Recognition and Stabilisation of the Parallel-stranded DNA Quadruplex d(TTAGGGT)4 Containing the Human Telomeric Repeat(2003)187 cited
- → Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A β-Sparing Phosphoinositide 3-Kinase Inhibitor with High Unbound Exposure and Robust in Vivo Antitumor Activity(2013)175 cited
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