Dean Bottino
Publications by Year
Research Areas
Cancer Genomics and Diagnostics, Statistical Methods in Clinical Trials, Chronic Lymphocytic Leukemia Research, Chronic Myeloid Leukemia Treatments, Computational Drug Discovery Methods
Most-Cited Works
- → How nematode sperm crawl(2002)209 cited
- → Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models(2019)80 cited
- → A computational model of ameboid deformation and locomotion(1998)76 cited
- → Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm(2020)70 cited
- → Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart(2005)69 cited
- → Modeling Viscoelastic Networks and Cell Deformation in the Context of the Immersed Boundary Method(1998)68 cited
- → BCR–ABL Transcript Dynamics Support the Hypothesis That Leukemic Stem Cells Are Reduced during Imatinib Treatment(2011)48 cited
- → A Phase I Monotherapy Study of RG7212, a First-in-Class Monoclonal Antibody Targeting TWEAK Signaling in Patients with Advanced Cancers(2014)46 cited
- → A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development(2023)40 cited
- → A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects(2019)35 cited