Sara H. Thrall
GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Epigenetics and DNA Methylation, RNA modifications and cancer, Cancer-related gene regulation, HIV Research and Treatment, Amino Acid Enzymes and Metabolism
Most-Cited Works
- → Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)(2012)485 cited
- → Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC(1997)132 cited
- → Mutant IDH1 Enhances the Production of 2-Hydroxyglutarate Due to Its Kinetic Mechanism(2013)83 cited
- → A Simple Assay for Detection of Small-Molecule Redox Activity(2007)68 cited
- → Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66(1997)66 cited
- → Development and Validation of Reagents and Assays for EZH2 Peptide and Nucleosome High-Throughput Screens(2012)60 cited
- → Imidazoquinoxaline Src-Family Kinase p56Lck Inhibitors: SAR, QSAR, and the Discovery of (S)-N-(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a Potent and Orally Active Inhibitor with Excellent in Vivo Antiinflammatory Activity(2004)55 cited
- → Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36(2016)55 cited
- → Evaluation of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Primer tRNA Binding by Fluorescence Spectroscopy: Specificity and Comparison to Primer/Template Binding(1996)43 cited
- → Chemical Mechanism of a Cysteine Protease, Cathepsin C, As Revealed by Integration of both Steady-State and Pre-Steady-State Solvent Kinetic Isotope Effects(2008)41 cited