Angela Smallwood
South College(US)GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Cancer, Hypoxia, and Metabolism, Atrial Fibrillation Management and Outcomes, Drug Transport and Resistance Mechanisms
Most-Cited Works
- → Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa(2007)391 cited
- → 1.56 Å structure of mature truncated human fibroblast collagenase(1994)185 cited
- → New IDH1 mutant inhibitors for treatment of acute myeloid leukemia(2015)176 cited
- → Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa(2001)172 cited
- → Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis(2013)135 cited
- → Structure-Based Design of Novel Guanidine/Benzamidine Mimics: Potent and Orally Bioavailable Factor Xa Inhibitors as Novel Anticoagulants(2003)96 cited