Cynthia Brimer
St. Jude Children's Research Hospital(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Hormonal Regulation and Hypertension, Estrogen and related hormone effects, Pharmacological Effects and Toxicity Studies
Most-Cited Works
- → Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression(2001)2,152 cited
- → Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450(2001)390 cited
- → Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D3(2001)325 cited
- → The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants(2001)290 cited
- → Environmental Xenobiotics and the Antihormones Cyproterone Acetate and Spironolactone Use the Nuclear Hormone Pregnenolone X Receptor to Activate the CYP3A23 Hormone Response Element(1998)153 cited
- → Cloning and Comparison of fliC Genes and Identification of Glycosylation in the Flagellin of Pseudomonas aeruginosa a-Type Strains(1998)121 cited
- → Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes(2000)107 cited
- → The Glucocorticoid Receptor Is Essential for Induction of Cytochrome P-4502B by Steroids but Not for Drug or Steroid Induction of CYP3A or P-450 Reductase in Mouse Liver(2000)103 cited
- → Creation of Polarized Cells Coexpressing CYP3A4, NADPH Cytochrome P450 Reductase and MDR1/P-glycoprotein(2000)39 cited
- → PharmGKB Update: II. CYP3A5, Cytochrome P450, Family 3, Subfamily A, Polypeptide 5(2004)33 cited