Leena Otsomaa
Orion Corporation (Finland)(FI)
Publications by Year
Research Areas
Cardiac electrophysiology and arrhythmias, Ion channel regulation and function, Cardiac pacing and defibrillation studies, Chemistry and Chemical Engineering, Heart Failure Treatment and Management
Most-Cited Works
- → ORM‐10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart(2013)71 cited
- → The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments(2016)63 cited
- → Long-Term Effects of Na+/Ca2+ Exchanger Inhibition with ORM-11035 Improves Cardiac Function and Remodelling without Lowering Blood Pressure in a Model of Heart Failure with Preserved Ejection Fraction(2019)27 cited
- → Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes(2017)14 cited
- → Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity(2020)14 cited
- → European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe**(2023)5 cited
- → Chapter 9. Medicinal Chemistry: How “Green” is Our Synthetic Tool Box?(2016)1 cited
- Design of selective Sodium Calcium Exchanger inhibitors for cardiac indications: - Chronic treatments and acute on/off use(2019)