Timothy P. C. Rooney
University of Cambridge(GB)Drug Discovery Laboratory (Norway)(NO)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, Histone Deacetylase Inhibitors Research, Ubiquitin and proteasome pathways, Peptidase Inhibition and Analysis
Most-Cited Works
- → Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains(2014)282 cited
- → Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions(2012)185 cited
- → Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions(2014)172 cited
- → A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction(2014)115 cited
- → Systematic Investigation of the Permeability of Androgen Receptor PROTACs(2020)68 cited
- → Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3(2016)31 cited
- → Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain(2021)26 cited
- → Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode(2022)19 cited
- → Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents(2024)18 cited
- → The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules(2022)14 cited