Steven T. Staben
Intarcia Therapeutics (United States)(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Protein Degradation and Inhibitors, Catalytic Alkyne Reactions, Ubiquitin and proteasome pathways, Chronic Lymphocytic Leukemia Research
Most-Cited Works
- → Gold(I)-Catalyzed Stereoselective Olefin Cyclopropanation(2005)525 cited
- → Gold(I)-Catalyzed Conia-Ene Reaction of β-Ketoesters with Alkynes(2004)426 cited
- → Gold(I)‐Catalyzed 5‐endo‐dig Carbocyclization of Acetylenic Dicarbonyl Compounds(2004)267 cited
- → Gold(I)‐Catalyzed Cyclizations of Silyl Enol Ethers: Application to the Synthesis of (+)‐Lycopladine A(2006)254 cited
- → Gold(I)-Catalyzed Ring Expansion of Cyclopropanols and Cyclobutanols(2005)222 cited
- → Au(I)-Catalyzed Ring Expanding Cycloisomerizations: Total Synthesis of Ventricosene(2008)177 cited
- → Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A β-Sparing Phosphoinositide 3-Kinase Inhibitor with High Unbound Exposure and Robust in Vivo Antitumor Activity(2013)175 cited
- → Selective activation of PFKL suppresses the phagocytic oxidative burst(2021)152 cited
- → MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition(2019)151 cited
- → Heterobifunctional Molecules Induce Dephosphorylation of Kinases–A Proof of Concept Study(2019)144 cited