Norman E. Wideburg
Abbott Fund(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Click Chemistry and Applications, HIV Research and Treatment, Chemical Synthesis and Analysis, Pneumocystis jirovecii pneumonia detection and treatment
Most-Cited Works
- → Design, Activity, and 2.8 Å Crystal Structure of a C 2 Symmetric Inhibitor Complexed to HIV-1 Protease(1990)528 cited
- → Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor(1994)213 cited
- → Structure-based, C2 symmetric inhibitors of HIV protease(1990)211 cited
- → Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy(1998)204 cited
- → Influence of stereochemistry on activity and binding modes for C2 symmetry-based diol inhibitors of HIV-1 protease(1994)133 cited
- → Symmetry-based inhibitors of HIV protease. Structure-activity studies of acylated 2,4-diamino-1,5-diphenyl-3-hydroxypentane and 2,5-diamino-1,6-diphenylhexane-3,4-diol(1993)130 cited
- → Synthetic chemical diversity: solid phase synthesis of libraries of C2 symmetric inhibitors of HIV protease containing diamino diol and diamino alcohol cores(1995)78 cited
- → Induction of calf thymus topoisomerase II-mediated DNA breakage by the antibacterial isothiazoloquinolones A-65281 and A-65282(1992)63 cited
- → A Novel, Picomolar Inhibitor of Human Immunodeficiency Virus Type 1 Protease(1996)62 cited
- → Design of orally bioavailable, symmetry-based inhibitors of HIV protease(1994)56 cited