Christine A. Pratilas
Johns Hopkins University(US)Johns Hopkins Medicine(US)Sidney Kimmel Comprehensive Cancer Center(US)University of Baltimore(US)
Publications by Year
Research Areas
Neurofibromatosis and Schwannoma Cases, Melanoma and MAPK Pathways, Neuroblastoma Research and Treatments, Sarcoma Diagnosis and Treatment, Advanced Breast Cancer Therapies
Most-Cited Works
- → BRAF mutation predicts sensitivity to MEK inhibition(2005)1,325 cited
- → V600E BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway(2009)613 cited
- → Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas(2012)556 cited
- → The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner(2010)446 cited
- → Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence(2014)308 cited
- → Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors(2012)290 cited