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Gordon J. Freeman

Harvard University(US)Dana-Farber Cancer Institute(US)

Publications by Year

Research Areas

Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, CAR-T cell therapy research, T-cell and B-cell Immunology

Most-Cited Works

→ Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response(2018)5,443 cited
→ PD-1 and Its Ligands in Tolerance and Immunity(2008)5,272 cited
→ Restoring function in exhausted CD8 T cells during chronic viral infection(2005)3,923 cited
→ PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma(2014)3,521 cited
→ PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression(2006)2,627 cited
→ THE B7 FAMILY REVISITED(2005)2,279 cited

→ CTLA-4 can function as a negative regulator of T cell activation(1994)

2,183 cited

→ Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection(2008)2,037 cited

→ PD-L1 regulates the development, maintenance, and function of induced regulatory T cells(2009)2,023 cited

→ Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy(2016)2,009 cited