Hillary L. Sturgis
Array BioPharma (United States)(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Protein Kinase Regulation and GTPase Signaling, HER2/EGFR in Cancer Research, Chronic Myeloid Leukemia Treatments, Cancer Mechanisms and Therapy
Most-Cited Works
- → Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition(2010)320 cited
- → Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors(2011)66 cited
- → Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships(2011)56 cited
- → Pyrazolopyridine inhibitors of B-RafV600E. Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors(2012)29 cited
- → Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase(2014)19 cited
- → Discovery of 2-Pyridylureas as Glucokinase Activators(2014)19 cited
- → The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase(2012)17 cited
- → Human B-Raf Kinase Domain bound to a Type II Pyrazolopyridine Inhibitor(2012)
- → Human B-Raf Kinase in Complex with an Amide Linked Pyrazolopyridine Inhibitor(2011)
- → B-Raf V600E Kinase Domain Bound to a Type II Dihydroquinazoline Inhibitor(2012)