Nicole Trainor
The University of Melbourne(AU)United States Military Academy(US)Walter and Eliza Hall Institute of Medical Research(AU)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Peptidase Inhibition and Analysis, Ubiquitin and proteasome pathways, Chromatin Remodeling and Cancer, Hepatitis C virus research
Most-Cited Works
- → BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design(2019)560 cited
- → Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity(2021)228 cited
- → Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor(2012)201 cited
- → A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo(2022)197 cited
- → Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor(2010)176 cited
- → Targeting cancer with small-molecule pan-KRAS degraders(2024)141 cited
- → Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions