Christopher J. Stubbs
AstraZeneca (Brazil)(BR)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Epigenetics and DNA Methylation, Ubiquitin and proteasome pathways, Antibiotics Pharmacokinetics and Efficacy, Protein Structure and Dynamics
Most-Cited Works
- → KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe(2019)93 cited
- → Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies(2019)85 cited
- → Using Ligand‐Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo‐Like Kinase 1(2012)82 cited
- → Specific inhibition of CK2α from an anchor outside the active site(2016)71 cited
- → From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo‐Like Kinase 1(2011)70 cited
- → Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase(2015)66 cited
- → Determination of Erythromycin in Serum and Urine by High-Performance Liquid Chromatography with Ultraviolet Detection(1985)61 cited
- → Mechanical Loading Promotes the Expansion of Primitive Osteoprogenitors and Organizes Matrix and Vascular Morphology in Long Bone Defects(2019)58 cited
- → Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors(2019)51 cited
- → Application of a Proteolysis/Mass Spectrometry Method for Investigating the Effects of Inhibitors on Hydroxylase Structure(2009)46 cited