Ivana Yen
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Colorectal Cancer Treatments and Studies, Cancer therapeutics and mechanisms, Lung Cancer Treatments and Mutations, Computational Drug Discovery Methods
Most-Cited Works
- → RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth(2010)1,616 cited
- → Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition(2016)258 cited
- → Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling(2014)249 cited
- → Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2(2016)214 cited
- → ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma(2021)133 cited
- → Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300(2016)94 cited
- → Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase(2013)90 cited
- → Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors(2018)72 cited
- → Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation(2014)61 cited
- → Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase(2013)60 cited