Dominic J. Reynolds
C4 Therapeutics (United States)(US)
Publications by Year
Research Areas
Fibroblast Growth Factor Research, Estrogen and related hormone effects, Kruppel-like factors research, Click Chemistry and Applications, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → 1,2-Diacetals: A New Opportunity for Organic Synthesis(2000)169 cited
- → H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma(2017)150 cited
- → The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action(2018)109 cited
- → Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer(2018)109 cited
- → Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)80 cited
- → Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)68 cited
- → The Total Synthesis of the Annonaceous Acetogenin, Muricatetrocin C(2002)55 cited
- → Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)(2011)54 cited
- → Effects of Shape on Thermodynamic Cyclizations of Cinchona Alkaloids(1999)48 cited
- → Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)(2013)41 cited