Matthew Jenks
Triangle(US)Scynexis (United States)(US)
Publications by Year
Research Areas
Trypanosoma species research and implications, HIV/AIDS drug development and treatment, Heat shock proteins research, Computational Drug Discovery Methods, Signaling Pathways in Disease
Most-Cited Works
- → SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis(2011)296 cited
- → Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents(2009)189 cited
- → Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis(2010)102 cited
- → Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90(2008)89 cited
- → Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90(2010)87 cited
- → Benzoxaboroles: A New Class of Potential Drugs for Human African Trypanosomiasis(2011)87 cited
- → Novel carbazole and acyl-indole antimitotics(2009)25 cited
- Efficacy and Pharmacokinetics of SCYX-7158 (AN5568): a Novel and Potent Oxaborole-6-Carboxamide Selected as a Pre-Clinical Candidate for Once-Daily Oral Treatment for Stage 2 Human African Trypanosomiasis.(2009)
- SCYX 7158: chemistry background and new findings.(2010)
- Lead Optimization of Novel Boron-Containing Drug Candidates for the Treatment of Human African Trypanosomiasis.(2009)