Massimiliano Fonsi
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Histone Deacetylase Inhibitors Research, MicroRNA in disease regulation
Most-Cited Works
- → Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors(2009)308 cited
- → Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders(2014)70 cited
- → Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors(2008)52 cited
- → Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties(2009)45 cited
- → High-Throughput Microsomal Stability Assay for Screening New Chemical Entities in Drug Discovery(2008)40 cited
- → Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 2(2011)37 cited
- → Intra-Articular Hyaluronic Acid and Chondroitin Sulfate: Pharmacokinetic Investigation in Osteoarthritic Rat Models(2019)35 cited
- → N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists(2011)25 cited
- → Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221(2019)19 cited
- → The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease(2010)17 cited