Björn Over
AstraZeneca (Sweden)(SE)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Microbial Natural Products and Biosynthesis, Drug Transport and Resistance Mechanisms, Bioactive Compounds and Antitumor Agents
Most-Cited Works
- → Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates(2014)769 cited
- → Natural-product-derived fragments for fragment-based ligand discovery(2012)300 cited
- → Cell permeability beyond the rule of 5(2016)282 cited
- → Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5(2018)212 cited
- → Structural and conformational determinants of macrocycle cell permeability(2016)209 cited
- → Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties(2014)86 cited
- → Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B(2011)53 cited
- → Mining Natural Products for Macrocycles to Drug Difficult Targets(2020)45 cited
- → Fragment‐Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition(2010)26 cited