Douglas S. Werner
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Click Chemistry and Applications, Cancer-related Molecular Pathways, PI3K/AKT/mTOR signaling in cancer, Receptor Mechanisms and Signaling
Most-Cited Works
- → Different apoptotic mechanisms are involved in the antiproliferative effects of 7β-hydroxysitosterol and 7β-hydroxycholesterol in human colon cancer cells(2004)70 cited
- → Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase(2020)39 cited
- → Imidazo[1,5-a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2(2011)22 cited
- → Reversible Linkage of Two Distinct Small Molecule Inhibitors of Myc Generates a Dimeric Inhibitor with Improved Potency That Is Active in Myc Over-Expressing Cancer Cell Lines(2015)17 cited
- → Is Protein Kinase Substrate Efficacy a Reliable Barometer for Successful Inhibitor Design?(1996)13 cited
- → A Novel, Nonpeptidic, Orally Active Bivalent Inhibitor of Human β-Tryptase(2018)11 cited
- → Discovery of an Orally Efficacious Imidazo[5,1-f][1,2,4]triazine Dual Inhibitor of IGF-1R and IR(2010)9 cited
- → Synthetic approaches to 5,7-disubstituted imidazo[5,1-f][1,2,4]triazin-4-amines(2010)7 cited
- → Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase(2018)7 cited
- → Abstract B43: Reversible linkage of two distinct small molecule inhibitors of MYC generates a more potent and selective dimeric inhibitor that is active in cancer cell lines over-expressing MYC(2015)