Wendell Wierenga
Crinetics Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Synthesis and Biological Evaluation, Synthesis and biological activity, Synthesis and Reactions of Organic Compounds, Synthesis and Characterization of Heterocyclic Compounds, Chemical Reaction Mechanisms
Most-Cited Works
- → Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065(1988)129 cited
- → Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. CI-1011: An Acyl Sulfamate with Unique Cholesterol-Lowering Activity in Animals Fed Noncholesterol-Supplemented Diets(1996)94 cited
- → General, efficient, one-step synthesis of .beta.-keto esters(1979)83 cited
- → AC220, a Potent, Selective, Second Generation FLT3 Receptor Tyrosine Kinase (RTK) Inhibitor, in a First-in-Human (FIH) Phase 1 AML Study.(2009)66 cited
- → Synthesis of the left-hand segment of the antitumor agent CC-1065(1981)59 cited
- → Synthesis of new, noncyclic ionophores exhibiting efficient calcium(2+) ion transport(1979)58 cited