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Clotilde Lagier‐Tourenne | doi.page

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Clotilde Lagier‐Tourenne

Broad Institute(US)Harvard University(US)Massachusetts General Hospital(US)

Publications by Year

Research Areas

Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, RNA Research and Splicing, Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology

Most-Cited Works

→ Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43(2011)1,346 cited
→ TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration(2010)1,001 cited
→ Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways(2015)976 cited
→ Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs(2012)742 cited
→ Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration(2019)642 cited
→ Rethinking ALS: The FUS about TDP-43(2009)585 cited

→ Animal models of neurodegenerative diseases(2018)

563 cited

→ Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration(2013)552 cited

→ Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs(2016)535 cited

→ ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43(2013)487 cited