Nancy-Ellen Haynes
La Roche College(US)
Publications by Year
Research Areas
Pancreatic function and diabetes, Metabolism, Diabetes, and Cancer, Diabetes Management and Research, Computational Drug Discovery Methods, Thyroid Disorders and Treatments
Most-Cited Works
- → Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy(2003)535 cited
- → Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia(2014)208 cited
- → Metal Impurities Cause False Positives in High-Throughput Screening Campaigns(2012)119 cited
- → Discovery of Piragliatin—First Glucokinase Activator Studied in Type 2 Diabetic Patients(2012)98 cited
- → Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)(2010)45 cited
- → Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes(2013)16 cited
- → Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor(2012)14 cited
- → Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors(2014)2 cited
- Development of fluorinated dehydroepiandrosterone analogues as inhibitors of mammalian glucose-6-phosphate dehydrogenase(1991)