Ruth Thompson
University of Sheffield(GB)
Publications by Year
Research Areas
DNA Repair Mechanisms, Microtubule and mitosis dynamics, Cancer-related Molecular Pathways, Cancer therapeutics and mechanisms, Cell death mechanisms and regulation
Most-Cited Works
- → The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design(2013)123 cited
- → Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy(2020)104 cited
- → Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo(2013)75 cited
- → A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase(2015)74 cited
- → NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus(2017)68 cited
- → The Mre11 Nuclease Is Critical for the Sensitivity of Cells to Chk1 Inhibition(2012)55 cited
- → An IRAK1–PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy(2019)54 cited
- → Suppression of Apoptosis by PIF1 Helicase in Human Tumor Cells(2011)42 cited
- → An Inhibitor of PIDDosome Formation(2015)40 cited
- → Treatment with the Chk1 inhibitor G�6976 enhances cisplatin cytotoxicity in SCLC cells(2011)25 cited