Michiko Tawada
Takeda (Japan)(JP)
Publications by Year
Research Areas
Neuropeptides and Animal Physiology, Computational Drug Discovery Methods, Diabetes Treatment and Management, Peptidase Inhibition and Analysis, Cellular Mechanics and Interactions
Most-Cited Works
- → TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma(2018)138 cited
- → Discovery of Potent Mcl-1/Bcl-xL Dual Inhibitors by Using a Hybridization Strategy Based on Structural Analysis of Target Proteins(2013)108 cited
- → Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors(2013)55 cited
- → Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: Discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics(2013)50 cited
- → Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554(2011)42 cited
- → Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitors(2012)41 cited
- → Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents(2017)35 cited
- → A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases(2012)30 cited
- → Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554(2011)28 cited
- → Design of potent dipeptidyl peptidase IV (DPP-4) inhibitors by employing a strategy to form a salt bridge with Lys554(2017)20 cited