Helen Huls
Amsterdam Neuroscience(NL)University of Amsterdam(NL)
Publications by Year
Research Areas
CAR-T cell therapy research, CRISPR and Genetic Engineering, Virus-based gene therapy research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction
Most-Cited Works
- → A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR(2012)513 cited
- → Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells(2016)443 cited
- → Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity(2015)395 cited
- → Toward eliminating HLA class I expression to generate universal cells from allogeneic donors(2013)302 cited
- → Redirecting Specificity of T-Cell Populations For CD19 Using the Sleeping Beauty System(2008)246 cited
- → Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies(2011)197 cited
- → Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor(2013)178 cited
- → Manufacture of Clinical-Grade CD19-Specific T Cells Stably Expressing Chimeric Antigen Receptor Using Sleeping Beauty System and Artificial Antigen Presenting Cells(2013)171 cited
- → Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses(2003)148 cited
- → piggyBac Transposon/Transposase System to Generate CD19-Specific T Cells for the Treatment of B-Lineage Malignancies(2009)137 cited