Will Somers
Pfizer (United States)(US)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, Protein purification and stability, Viral Infectious Diseases and Gene Expression in Insects, Adenosine and Purinergic Signaling
Most-Cited Works
- → Improved variants of SrtA for site-specific conjugation on antibodies and proteins with high efficiency(2016)125 cited
- → Two N-Terminal Domains of Kv4 K+ Channels Regulate Binding to and Modulation by KChIP1(2004)118 cited
- → Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins(2018)44 cited
- → CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery(2013)33 cited
- → Engineering novel Lec1 glycosylation mutants in CHO–DUKX cells: Molecular insights and effector modulation of N‐acetylglucosaminyltransferase I(2012)32 cited
- → Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing(2018)30 cited
- → A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv)(2015)24 cited
- → Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates(2022)22 cited
- → Pyroglutamate and O-Linked Glycan Determine Functional Production of Anti-IL17A and Anti-IL22 Peptide-Antibody Bispecific Genetic Fusions(2012)20 cited
- → Mechanistic understanding of the cysteine capping modifications of antibodies enables selective chemical engineering in live mammalian cells(2017)19 cited