Shinya Hisakawa
Shionogi (Japan)(JP)Futaba (Japan)(JP)
Publications by Year
Research Areas
Histone Deacetylase Inhibitors Research, Peptidase Inhibition and Analysis, Antibiotic Resistance in Bacteria, Chemical Synthesis and Analysis, Protein Degradation and Inhibitors
Most-Cited Works
- → Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship(2018)158 cited
- → Highly Potent and Selective Histone Deacetylase 6 Inhibitors Designed Based on a Small-Molecular Substrate(2006)104 cited
- → Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors(2007)52 cited
- → Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent(2005)26 cited
- → Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor(2007)18 cited
- → Synthesis of a 6-CF3-Substituted 2-Amino-dihydro-1,3-thiazine β-Secretase Inhibitor by N,N-Diethylaminosulfur Trifluoride-Mediated Chemoselective Cyclization(2018)13 cited
- → Stereoselective and Scalable Synthesis of Potent Antibiotic RSC-435830 Through a Key Intermediate C2 (S)-Methylcephalosporin(2025)
- → CCDC 1861093: Experimental Crystal Structure Determination(2019)
- P-440 DISCOVERY OF NOVEL HISTONE DEACETYLASE 6 SELECTIVE INHIBITORS(2006)