Helen Chapman
GlaxoSmithKline (United Kingdom)(GB)
Publications by Year
Research Areas
Adipose Tissue and Metabolism, Receptor Mechanisms and Signaling, Pharmacological Effects and Assays, Neuroscience and Neuropharmacology Research, Parkinson's Disease Mechanisms and Treatments
Most-Cited Works
- → Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean(2000)613 cited
- → A selective orexin-1 receptor antagonist reduces food consumption in male and female rats(2000)338 cited
- Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma.(1998)
- → The Basal Proton Conductance of Skeletal Muscle Mitochondria from Transgenic Mice Overexpressing or Lacking Uncoupling Protein-3(2002)201 cited
- → Differential Regulation of Adipocytokine mRNAs by Rosiglitazone in db/db Mice(2001)151 cited
- → Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice(2002)139 cited
- → The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B(2008)118 cited
- → Novel α2-adrenoceptor antagonists show selectivity for α2A- and α2B-adrenoceptor subtypes(1989)108 cited
- → Identification of High-Affinity Binding Sites for the Insulin Sensitizer Rosiglitazone (BRL-49653) in Rodent and Human Adipocytes Using a Radioiodinated Ligand for Peroxisomal Proliferator-Activated Receptor γ(1998)101 cited
- The contribution of classical (beta1/2-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta3-adrenoceptor agonists of differing selectivities.(1998)