Owen Callaghan
Benedictine College(US)
Publications by Year
Research Areas
Chemical synthesis and alkaloids, Amino Acid Enzymes and Metabolism, Radical Photochemical Reactions, Enzyme Structure and Function, Enzyme Production and Characterization
Most-Cited Works
- → Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency(2007)211 cited
- → Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency(2010)185 cited
- → Application of Fragment Screening by X-ray Crystallography to β-Secretase(2007)144 cited
- → Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase(2007)142 cited
- → A novel total synthesis of (±)-aspidospermidine(1999)81 cited
- → Kinetic studies on rabbit-muscle myokinase(1959)54 cited
- → Tandem Radical Cyclizations on Iodoaryl Azides: Synthesis of the Core Tetracycle of Aspidosperma Alkaloids(1999)53 cited
- → A novel route to (±)-aspidospermidine: First application of “radical-polar crossover” reactions to total synthesis(1999)48 cited
- → Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator(2007)48 cited
- → CHEMICAL POLLUTANTS IN RELATION TO DISEASES IN FISH*(1977)36 cited