Krista L. Dobo
Pfizer (United States)(US)PRX Research
Publications by Year
Research Areas
Carcinogens and Genotoxicity Assessment, Computational Drug Discovery Methods, Effects and risks of endocrine disrupting chemicals, Water Treatment and Disinfection, Pesticide Exposure and Toxicity
Most-Cited Works
- → In silico toxicology protocols(2018)237 cited
- → The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development(2006)127 cited
- → Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities(2013)125 cited
- → Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses(2016)109 cited
- → In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey(2012)84 cited
- → Establishing best practise in the application of expert review of mutagenicity under ICH M7(2015)81 cited
- → Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities(2022)80 cited
- → Genetic toxicology in silico protocol(2019)78 cited
- → Permitted daily exposure limits for noteworthy N‐nitrosamines(2021)68 cited
- → Defining EMS and ENU dose–response relationships using the Pig-a mutation assay in rats(2011)48 cited