Alex N. Bullock
Discovery Centre(CA)
Publications by Year
Research Areas
Enzyme Structure and Function, Ubiquitin and proteasome pathways, Cancer Mechanisms and Therapy, Cancer-related Molecular Pathways, Heterotopic Ossification and Related Conditions
Most-Cited Works
- → Targeted protein degradation: expanding the toolbox(2019)894 cited
- → Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family(2002)710 cited
- → Rescuing the function of mutant p53(2001)578 cited
- → Structural basis of Keap1 interactions with Nrf2(2015)571 cited
- → Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma(2014)519 cited
- → Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy(2000)433 cited
- → Thermodynamic stability of wild-type and mutant p53 core domain(1997)417 cited
- → CIS is a potent checkpoint in NK cell–mediated tumor immunity(2016)377 cited
- → A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases(2007)375 cited
- → Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors(2016)363 cited