Kenton L. Longenecker
AbbVie (United States)(US)
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Diabetes Treatment and Management, Neuropeptides and Animal Physiology, Enzyme Structure and Function, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer(2020)393 cited
- → The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity(2023)151 cited
- → Three-dimensional Structure of Mammalian Casein Kinase I: Molecular Basis for Phosphate Recognition(1996)132 cited
- → Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI(2001)123 cited
- → Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain(2020)117 cited
- → Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5(2017)98 cited
- → The Effect of Ionic Liquids on Protein Crystallization and X-ray Diffraction Resolution(2009)94 cited
- → Discovery and Structure−Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors(2007)89 cited
- → Structure of the RGS-like Domain from PDZ-RhoGEF(2001)74 cited
- → How RhoGDI binds Rho(1999)73 cited