Jeffrey S. Albert
Case Western Reserve University(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, Neuropeptides and Animal Physiology, Analytical Chemistry and Chromatography
Most-Cited Works
- → Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency(2007)211 cited
- → Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation(2007)148 cited
- → Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase(2007)142 cited
- → An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes(2007)127 cited
- → Mechanistic studies of alkene epoxidation catalyzed by nickel(II) cyclam complexes. Oxygen-18 labeling and substituent effects(1988)121 cited
- → Stabilization of Helical Domains in Short Peptides Using Hydrophobic Interactions(1995)91 cited
- → Molecular Recognition of Proteins: Sequence-Selective Binding of Aspartate Pairs in Helical Peptides(1995)87 cited
- → Synthetic analogs of the ristocetin binding site: Neutral, multidentate receptors for carboxylate recognition(1993)54 cited
- → Design, Synthesis, and SAR of Tachykinin Antagonists: Modulation of Balance in NK1/NK2 Receptor Antagonist Activity(2002)51 cited
- → Discovery of novel, orally active dual NK1/NK2 antagonists(2001)39 cited