James T. Wasicak
Abbott Fund(US)
Publications by Year
Research Areas
Nicotinic Acetylcholine Receptors Study, Cholinesterase and Neurodegenerative Diseases, Chemical synthesis and alkaloids, Receptor Mechanisms and Signaling, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → Novel 3-Pyridyl Ethers with Subnanomolar Affinity for Central Neuronal Nicotinic Acetylcholine Receptors(1996)231 cited
- → A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: In Vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand(1996)137 cited
- → Identification and Initial Structure−Activity Relationships of (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors(1998)131 cited
- → ABT-594 [(R)-5-(2-Azetidinylmethoxy)-2-Chloropyridine]: A Novel, Orally Effective Analgesic Acting via Neuronal Nicotinic Acetylcholine Receptors: I. In Vitro Characterization(1998)103 cited
- → Novel Isoxazoles which Interact with Brain Cholinergic Channel Receptors Have Intrinsic Cognitive Enhancing and Anxiolytic Activities(1994)88 cited
- → Conformationally constrained amino acids. Synthesis and optical resolution of 3-substituted proline derivatives(1990)80 cited
- → ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: A Novel, Orally Effective Antinociceptive Agent Acting via Neuronal Nicotinic Acetylcholine Receptors: II. In Vivo Characterization(1998)77 cited
- → Ligands for Brain Cholinergic Channel Receptors: Synthesis and in Vitro Characterization of Novel Isoxazoles and Isothiazoles as Bioisosteric Replacements for the Pyridine Ring in Nicotine(1994)62 cited
- → Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: Effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice(1998)53 cited
- → Characterization of [3H]ABT-418: a novel cholinergic channel ligand.(1995)32 cited