D. Scherzer
GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Epigenetics and DNA Methylation, Synthesis and biological activity, PI3K/AKT/mTOR signaling in cancer, Melanoma and MAPK Pathways, Cancer-related gene regulation
Most-Cited Works
- → Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2(2012)375 cited
- → Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors(2011)54 cited
- → Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors(2008)52 cited
- → Abstract 2939: Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2(2012)1 cited
- → Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 1,1-Dimethylethyl {(3R,6S)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-3-piperidinyl}carbamate(2011)
- → Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-(3-Amino-1H-indazol-6-yl)-N4-ethyl-2,4-pyrimidinediamine(2011)
- → Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-N-phenyl-2-morpholinecarboxamide(2011)