Anke Steinbach
Helmholtz Institute for Pharmaceutical Research Saarland(DE)
Publications by Year
Research Areas
Bacterial Genetics and Biotechnology, Bacterial biofilms and quorum sensing, Antibiotic Resistance in Bacteria, Antimicrobial Resistance in Staphylococcus, Computational Drug Discovery Methods
Most-Cited Works
- → Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors(2014)199 cited
- → Interfering with Bacterial Quorum Sensing(2016)126 cited
- → Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors(2012)121 cited
- → Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa(2012)120 cited
- → Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in Pseudomonas aeruginosa : An In Vivo Potent Antivirulence Agent Targeting pqs Quorum Sensing(2013)96 cited
- → Identification of Small-Molecule Antagonists of the Pseudomonas aeruginosa Transcriptional Regulator PqsR: Biophysically Guided Hit Discovery and Optimization(2012)72 cited
- → Discovery and Biophysical Characterization of 2-Amino-oxadiazoles as Novel Antagonists of PqsR, an Important Regulator of Pseudomonas aeruginosa Virulence(2013)61 cited
- → Structure Optimization of 2-Benzamidobenzoic Acids as PqsD Inhibitors for Pseudomonas aeruginosa Infections and Elucidation of Binding Mode by SPR, STD NMR, and Molecular Docking(2013)53 cited
- → Optimization of anti-virulence PqsR antagonists regarding aqueous solubility and biological properties resulting in new insights in structure–activity relationships(2014)46 cited
- → The Unusual Binding Mode of Cnicin to the Antibacterial Target Enzyme MurA Revealed by X-ray Crystallography(2008)37 cited