Aaron Kunzer
AbbVie (United States)(US)
Publications by Year
Research Areas
Cell death mechanisms and regulation, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis
Most-Cited Works
- → An inhibitor of Bcl-2 family proteins induces regression of solid tumours(2005)3,369 cited
- → Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL(2007)294 cited
- → Discovery of an Orally Bioavailable Small Molecule Inhibitor of Prosurvival B-Cell Lymphoma 2 Proteins(2008)291 cited
- → Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo(2006)130 cited
- → Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-XL Inhibitor(2020)127 cited
- → Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment‐based Design Strategies(2007)118 cited
- → Discovery of a novel small molecule binding site of human survivin(2007)81 cited
- → Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein(2014)80 cited
- → Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients(2023)55 cited
- → A Facile One-Carbon Homologation of Aryl Aldehydes to Amides(2002)37 cited