Zhe Nie
Schrodinger (United States)(US)
Publications by Year
Research Areas
Chronic Lymphocytic Leukemia Research, Biochemical and Molecular Research, Computational Drug Discovery Methods, Cancer-related Molecular Pathways, Histone Deacetylase Inhibitors Research
Most-Cited Works
- → Structure-Based Design, Synthesis, and Antimicrobial Activity of Indazole-Derived SAH/MTA Nucleosidase Inhibitors(2003)160 cited
- → Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)(2020)116 cited
- → Structure-Based Design, Synthesis, and Study of Potent Inhibitors of β-Ketoacyl-acyl Carrier Protein Synthase III as Potential Antimicrobial Agents(2005)97 cited
- → Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities(2007)97 cited
- → Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2(2007)95 cited
- → TAK-960, a Novel, Orally Available, Selective Inhibitor of Polo-Like Kinase 1, Shows Broad-spectrum Preclinical Antitumor Activity in Multiple Dosing Regimens(2011)77 cited
- → Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK)(2016)60 cited
- → Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme(2009)58 cited
- → Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1)(2013)48 cited
- → Structure-based design and discovery of potent and selective KDM5 inhibitors(2018)38 cited