Srinivasa M. Srinivasula
Publications by Year
Research Areas
Cell death mechanisms and regulation, Autophagy in Disease and Therapy, NF-κB Signaling Pathways, Mitochondrial Function and Pathology, RNA Interference and Gene Delivery
Most-Cited Works
- → Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade(1997)7,227 cited
- → Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells(2000)1,196 cited
- → Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization(1998)1,125 cited
- → A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis(2001)997 cited
- → Negative regulation of the Apaf-1 apoptosome by Hsp70(2000)818 cited
- → In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.(1996)732 cited
- → Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction(2002)730 cited
- → Mechanism of XIAP-Mediated Inhibition of Caspase-9(2003)726 cited
- → Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation(2006)597 cited
- → The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1(2002)565 cited