Jana Sopková‐de Oliveira Santos
Normandie Université(FR)Université de Caen Normandie(FR)
Publications by Year
Research Areas
Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Cholinesterase and Neurodegenerative Diseases
Most-Cited Works
- → Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride(2015)115 cited
- → Structure of Membrane-bound Annexin A5 Trimers: A Hybrid Cryo-EM - X-ray Crystallography Study(2000)92 cited
- → Synthesis of novel halopyridinylboronic acids and esters. Part 4: Halopyridin-2-yl-boronic acids and esters are stable, crystalline partners for classical Suzuki cross-coupling(2003)92 cited
- → Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action(2006)91 cited
- → Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation(2017)91 cited
- → Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity