Richard W. Friesen
Merck Canada Inc. (Canada)(CA)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Inflammatory mediators and NSAID effects, Asymmetric Synthesis and Catalysis, Catalytic Cross-Coupling Reactions, Carbohydrate Chemistry and Synthesis
Most-Cited Works
- → Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2(2001)457 cited
- → Quinolines as potent 5-lipoxygenase inhibitors: Synthesis and biological profile of L-746,530(1998)271 cited
- → On the controlled oxidative coupling of glycals: a new strategy for the rapid assembly of oligosaccharides(1989)179 cited
- → Biaryl synthesis via suzuki coupling on a solid support(1994)174 cited
- → MF63 [2-(6-Chloro-1 H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation(2008)152 cited
- → Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886(2005)142 cited
- → 2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors(1998)128 cited
- → Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors(2007)128 cited
- → The C3a receptor antagonist SB 290157 has agonist activity(2005)92 cited
- → The preparation of C-arylglycals. The palladium-catalyzed coupling of 3,4,6-tri-O-(tert-butyldimethylsilyl)-1-(tributylstannyl)-D-glucal and aryl bromides(1990)87 cited