Tobias Schmelzle
Novartis (Switzerland)(CH)
Publications by Year
Research Areas
Hippo pathway signaling and YAP/TAZ, CRISPR and Genetic Engineering, Fungal and yeast genetics research, PI3K/AKT/mTOR signaling in cancer, Plant Surface Properties and Treatments
Most-Cited Works
- → TOR, a Central Controller of Cell Growth(2000)1,914 cited
- → Engineering tumors with 3D scaffolds(2007)814 cited
- → Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening(2017)693 cited
- → Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5(2016)552 cited
- → YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers(2015)420 cited
- → CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions(2016)395 cited
- → Activation of the RAS/Cyclic AMP Pathway Suppresses a TOR Deficiency in Yeast(2003)263 cited
- → YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors(2015)245 cited
- → TIP41 Interacts with TAP42 and Negatively Regulates the TOR Signaling Pathway(2001)236 cited
- → BIM Regulates Apoptosis during Mammary Ductal Morphogenesis, and Its Absence Reveals Alternative Cell Death Mechanisms(2007)233 cited