Thomas Macartney
University of Dundee(GB)MRC Protein Phosphorylation and Ubiquitylation Unit(GB)Office of Diversity and Inclusion(US)Medical Research Council(GB)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Peptidase Inhibition and Analysis, Cellular transport and secretion, DNA Repair Mechanisms
Most-Cited Works
- → PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65(2012)928 cited
- → 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization(2010)398 cited
- → Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair(2009)333 cited
- → Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2(2010)317 cited
- → The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction(2013)219 cited
- → The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human(2018)215 cited