Alden C. Klarer
New Jersey Institute of Technology(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Cancer-related Molecular Pathways, Metabolism, Diabetes, and Cancer, CAR-T cell therapy research, DNA Repair Mechanisms
Most-Cited Works
- → Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer(2013)274 cited
- → 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27(2014)203 cited
- → Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism(2014)100 cited
- → Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth(2014)95 cited
- → Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation(2012)93 cited
- → Phase II trial of the regulatory T cell-depleting agent, denileukin diftitox, in patients with unresectable stage IV melanoma(2011)76 cited
- → Clinical development of cancer therapeutics that target metabolism(2015)32 cited
- → Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth(2012)22 cited
- → Replication of Damaged Genomes(2011)21 cited
- → DNA Polymerase Eta Participates in the Mutagenic Bypass of Adducts Induced by Benzo[a]pyrene Diol Epoxide in Mammalian Cells(2012)16 cited