Alex Cazes
AstraZeneca (United States)(US)
Publications by Year
Research Areas
Neuroblastoma Research and Treatments, Cancer, Hypoxia, and Metabolism, Cancer Cells and Metastasis, Liver physiology and pathology, Cancer Research and Treatments
Most-Cited Works
- → Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma(2014)107 cited
- → Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment(2015)84 cited
- → An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein(2014)75 cited
- → The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking(2011)65 cited
- → Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma(2012)65 cited
- → Breakpoint Features of Genomic Rearrangements in Neuroblastoma with Unbalanced Translocations and Chromothripsis(2013)43 cited
- → A MET Targeting Antibody–Drug Conjugate Overcomes Gemcitabine Resistance in Pancreatic Cancer(2021)34 cited
- → Internalization and Down-Regulation of the ALK Receptor in Neuroblastoma Cell Lines upon Monoclonal Antibodies Treatment(2012)34 cited
- → MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages(2019)31 cited
- → The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies(2022)31 cited