Thomas N. Nanninga
Pfizer (United States)(US)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Cyclopropane Reaction Mechanisms, Chemical Synthesis and Analysis, Oxidative Organic Chemistry Reactions, Catalytic C–H Functionalization Methods
Most-Cited Works
- → The convergent synthesis of CI-981, an optically active, highly potent, tissue selective inhibitor of HMG-CoA reductase(1992)122 cited
- → The synthesis of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, a key intermediate for the preparation of CI-981, a highly potent, tissue selective inhibitor of HMG-CoA reductase(1992)99 cited
- → Development of a Scalable Process for CI-1034, an Endothelin Antagonist(2004)55 cited
- → Palladium-mediated cycloaddition approach to loganin aglucon(1985)51 cited
- → Chemoselectivity in palladium-mediated cycloadditions of substituted trimethylenemethanes(1985)50 cited
- → 2-[(Trimethylsilyl)methyl]-1-(trimethylsilyl)propen-3-yl carboxylates in cycloaddition. Novel approach for substitutive cyclopentannulation(1988)46 cited
- → Molecular orbital study of substituted trimethylenemethane-bis(phosphine)palladium complexes(1981)40 cited
- → Regiochemistry of cycloaddition of (trimethylenemethane)palladium intermediates to muconic esters(1982)37 cited
- → Diastereoselective, large scale synthesis of β-amino acids via asymmetric enamide hydrogenation as α2δ ligands for the treatment of generalized anxiety disorder and insomnia(2009)22 cited
- → Heterocyclic Acceptors in Diastereoselective Palladium Mediated [3+2] Cycloadditions(1987)20 cited