Ed Cleator
Janssen (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis, Marine Sponges and Natural Products, Crystallization and Solubility Studies
Most-Cited Works
- → Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)(2011)122 cited
- → The First Large-Scale Synthesis of MK-4305: A Dual Orexin Receptor Antagonist for the Treatment of Sleep Disorder(2011)100 cited
- → Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub‐Nanomolar SERCA Inhibition(2007)90 cited
- → Intramolecular Cyclopropanation of Unsaturated Terminal Epoxides and Chlorohydrins(2007)86 cited
- → Total synthesis of (−)-nakadomarin A(2011)84 cited
- → Total Synthesis of Thapsigargin, a Potent SERCA Pump Inhibitor(2007)80 cited
- → Synthesis of the thapsigargins(2004)77 cited
- → A concise total synthesis of (+)-okaramine C(2004)77 cited
- → The Synthesis of Azadirachtin: A Potent Insect Antifeedant(2008)64 cited
- → Asymmetric Synthesis of cis-2,5-Disubstituted Pyrrolidine, the Core Scaffold of β3-AR Agonists(2013)54 cited