Richard J. Perner

Publications by Year

Research Areas

Ion Channels and Receptors, Pain Mechanisms and Treatments, Ion channel regulation and function, Receptor Mechanisms and Signaling, Synthesis and Reactivity of Heterocycles

Most-Cited Works

• → Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation(2011)269 cited
• → TRPA1 Modulation of Spontaneous and Mechanically Evoked Firing of Spinal Neurons in Uninjured, Osteoarthritic, and Inflamed Rats(2010)192 cited
• → Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain: Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties(2005)163 cited
• → A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets(1992)156 cited
• → Discovery of 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine, an Orally Active, Non-Nucleoside Adenosine Kinase Inhibitor(2001)79 cited
• → A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model(2010)64 cited
• → Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor(1991)63 cited
• → Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa.(1995)46 cited
• → The enantioselective synthesis of the potent dopamine D1 agonist (1R,3S)-3-(1'-adamantyl)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran (A77636)(1992)44 cited
• → Adenosine kinase inhibitors: polar 7-Substitutent of pyridopyrimidine derivatives improving their locomotor selectivity(2003)43 cited